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1.

Direct-Acting Antiviral Therapy for Patients with Chronic Hepatitis C Infection and Decompensated Cirrhosis.

Pearlman, Brian L.

Dig Dis Sci ; 2024 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-38580885

2.

Hepatitis Delta Infection: A Clinical Review.

Pearlman, Brian.

Semin Liver Dis ; 43(3): 293-304, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37473778

3.

A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study.

Sulkowski, Mark S; Moon, Juhi S; Sherman, Kenneth E; Morelli, Giuseppe; Darling, Jama M; Muir, Andrew J; Khalili, Mandana; Fishbein, Dawn A; Hinestrosa, Federico; Shiffman, Mitchell L; Di Bisceglie, Adrian; Rajender Reddy, K; Pearlman, Brian; Lok, Anna S; Fried, Michael W; Stewart, Paul W; Peter, Joy; Wadsworth, Summer; Kixmiller, Scott; Sloan, Anquenette; Vainorius, Monika; Horne, Patrick M; Michael, Larry; Dong, Meichen; Evon, Donna M; Segal, Jodi B; Nelson, David R.

Hepatology ; 74(6): 2952-2964, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34255381

4.

Efficacy of Glecaprevir and Pibrentasvir in Patients With Genotype 1 Hepatitis C Virus Infection With Treatment Failure After NS5A Inhibitor Plus Sofosbuvir Therapy.

Lok, Anna S; Sulkowski, Mark S; Kort, Jens J; Willner, Ira; Reddy, K Rajender; Shiffman, Mitchell L; Hassan, Mohamed A; Pearlman, Brian L; Hinestrosa, Federico; Jacobson, Ira M; Morelli, Giuseppe; Peter, Joy A; Vainorius, Monika; Michael, Larry C; Fried, Michael W; Wang, Gary P; Lu, Wenjing; Larsen, Lois; Nelson, David R.

Gastroenterology ; 157(6): 1506-1517.e1, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31401140

5.

Sofosbuvir/Velpatasvir/Voxilaprevir for Previous Treatment Failures With Glecaprevir/Pibrentasvir in Chronic Hepatitis C Infection.

Pearlman, Brian; Perrys, Michael; Hinds, Andrew.

Am J Gastroenterol ; 114(9): 1550-1552, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31082871

6.

Erratum to: Hepatitis Delta Infection: A Clinical Review.

Pearlman, Brian.

Semin Liver Dis ; 43(3): e1, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37816394

7.

Effectiveness of Elbasvir and Grazoprevir Combination, With or Without Ribavirin, for Treatment-Experienced Patients With Chronic Hepatitis C Infection.

Kwo, Paul; Gane, Edward J; Peng, Cheng-Yuan; Pearlman, Brian; Vierling, John M; Serfaty, Lawrence; Buti, Maria; Shafran, Stephen; Stryszak, Paul; Lin, Li; Gress, Jacqueline; Black, Stuart; Dutko, Frank J; Robertson, Michael; Wahl, Janice; Lupinacci, Lisa; Barr, Eliav; Haber, Barbara.

Gastroenterology ; 152(1): 164-175.e4, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27720838

8.

Efficacy of 8 Weeks of Sofosbuvir, Velpatasvir, and Voxilaprevir in Patients With Chronic HCV Infection: 2 Phase 3 Randomized Trials.

Jacobson, Ira M; Lawitz, Eric; Gane, Edward J; Willems, Bernard E; Ruane, Peter J; Nahass, Ronald G; Borgia, Sergio M; Shafran, Stephen D; Workowski, Kimberly A; Pearlman, Brian; Hyland, Robert H; Stamm, Luisa M; Svarovskaia, Evguenia; Dvory-Sobol, Hadas; Zhu, Yanni; Subramanian, G Mani; Brainard, Diana M; McHutchison, John G; Bräu, Norbert; Berg, Thomas; Agarwal, Kosh; Bhandari, Bal Raj; Davis, Mitchell; Feld, Jordan J; Dore, Gregory J; Stedman, Catherine A M; Thompson, Alexander J; Asselah, Tarik; Roberts, Stuart K; Foster, Graham R.

Gastroenterology ; 153(1): 113-122, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28390869

9.

Elbasvir/grazoprevir in black adults with hepatitis C virus infection: a pooled analysis of phase 2/3 clinical trials.

Zamor, Philippe J; Vierling, John; Ghalib, Reem; Luketic, Velimir; Ravendhran, Natarajan; Balart, Luis; Robertson, Michael; Hwang, Peggy; Hanna, George J; Nguyen, Bach-Yen; Barr, Eliav; Talwani, Rohit; Pearlman, Brian.

Am J Gastroenterol ; 113(6): 863-871, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29695828

10.

Renin secreting tumour: a rare cause of secondary hypertension.

Pearlman, Brian; Lodebo, Bereket T.

Lancet ; 398(10305): 1074, 2021 09 18.

Artigo em Inglês | MEDLINE | ID: mdl-34537092

11.

Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial.

Lawitz, Eric; Reau, Nancy; Hinestrosa, Federico; Rabinovitz, Mordechai; Schiff, Eugene; Sheikh, Aasim; Younes, Ziad; Herring, Robert; Reddy, K Rajender; Tran, Tram; Bennett, Michael; Nahass, Ronald; Yang, Jenny C; Lu, Sophia; Dvory-Sobol, Hadas; Stamm, Luisa M; Brainard, Diana M; McHutchison, John G; Pearlman, Brian; Shiffman, Mitchell; Hawkins, Trevor; Curry, Michael; Jacobson, Ira.

Gastroenterology ; 151(5): 893-901.e1, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27486034

12.

A Patient With Jaundice and Malaise.

Pearlman, Brian L.

JAMA ; 327(24): 2448-2449, 2022 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-35696255

13.

Efficacy and safety of 12 weeks versus 18 weeks of treatment with grazoprevir (MK-5172) and elbasvir (MK-8742) with or without ribavirin for hepatitis C virus genotype 1 infection in previously untreated patients with cirrhosis and patients with previous null response with or without cirrhosis (C-WORTHY): a randomised, open-label phase 2 trial.

Lawitz, Eric; Gane, Edward; Pearlman, Brian; Tam, Edward; Ghesquiere, Wayne; Guyader, Dominique; Alric, Laurent; Bronowicki, Jean-Pierre; Lester, Laura; Sievert, William; Ghalib, Reem; Balart, Luis; Sund, Fredrik; Lagging, Martin; Dutko, Frank; Shaughnessy, Melissa; Hwang, Peggy; Howe, Anita Y M; Wahl, Janice; Robertson, Michael; Barr, Eliav; Haber, Barbara.

Lancet ; 385(9973): 1075-86, 2015 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-25467591

14.

The combination of simeprevir and sofosbuvir is more effective than that of peginterferon, ribavirin, and sofosbuvir for patients with hepatitis C-related Child's class A cirrhosis.

Pearlman, Brian L; Ehleben, Carole; Perrys, Michael.

Gastroenterology ; 148(4): 762-70.e2; quiz e11-2, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25557952

15.

Daclatasvir and Peginterferon/Ribavirin for Black/African-American and Latino Patients with HCV infection.

Rodriguez-Torres, Maribel; Lawitz, Eric; Yangco, Bienvenido; Jeffers, Lennox; Han, Steven-Huy; Thuluvath, Paul J; Rustgi, Vinod; Harrison, Stephen; Ghalib, Reem; Vierling, John M; Luketic, Velimir; Zamor, Philippe J; Ravendhran, Natarajan; Morgan, Timothy R; Pearlman, Brian; O'Brien, Christopher; Khallafi, Hicham; Pyrsopoulos, Nikolaos; Kong, George; McPhee, Fiona; Yin, Philip D; Hughes, Eric; Treitel, Michelle.

Ann Hepatol ; 15(6): 834-845, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27740516

16.

Safety profile of boceprevir and telaprevir in chronic hepatitis C: real world experience from HCV-TARGET.

Gordon, Stuart C; Muir, Andrew J; Lim, Joseph K; Pearlman, Brian; Argo, Curtis K; Ramani, Ananthakrishnan; Maliakkal, Benedict; Alam, Imtiaz; Stewart, Thomas G; Vainorius, Monika; Peter, Joy; Nelson, David R; Fried, Michael W; Reddy, K Rajender.

J Hepatol ; 62(2): 286-93, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25218788

17.

Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.

Lawitz, Eric; Sulkowski, Mark S; Ghalib, Reem; Rodriguez-Torres, Maribel; Younossi, Zobair M; Corregidor, Ana; DeJesus, Edwin; Pearlman, Brian; Rabinovitz, Mordechai; Gitlin, Norman; Lim, Joseph K; Pockros, Paul J; Scott, John D; Fevery, Bart; Lambrecht, Tom; Ouwerkerk-Mahadevan, Sivi; Callewaert, Katleen; Symonds, William T; Picchio, Gaston; Lindsay, Karen L; Beumont, Maria; Jacobson, Ira M.

Lancet ; 384(9956): 1756-65, 2014 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-25078309

18.

Hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor.

Pearlman, Brian L; Ehleben, Carole.

Hepatology ; 59(1): 71-7, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23873583

19.

How Would You Manage This Patient With Nonalcoholic Fatty Liver Disease?

Pearlman, Brian L.

Ann Intern Med ; 171(11): 861-862, 2019 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-31791051

20.

Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more.

Pearlman, Brian L; Traub, Nomi.

Clin Infect Dis ; 52(7): 889-900, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21427396

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Direct-Acting Antiviral Therapy for Patients with Chronic Hepatitis C Infection and Decompensated Cirrhosis.

Hepatitis Delta Infection: A Clinical Review.

A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study.

Efficacy of Glecaprevir and Pibrentasvir in Patients With Genotype 1 Hepatitis C Virus Infection With Treatment Failure After NS5A Inhibitor Plus Sofosbuvir Therapy.

Sofosbuvir/Velpatasvir/Voxilaprevir for Previous Treatment Failures With Glecaprevir/Pibrentasvir in Chronic Hepatitis C Infection.

Erratum to: Hepatitis Delta Infection: A Clinical Review.

Effectiveness of Elbasvir and Grazoprevir Combination, With or Without Ribavirin, for Treatment-Experienced Patients With Chronic Hepatitis C Infection.

Efficacy of 8 Weeks of Sofosbuvir, Velpatasvir, and Voxilaprevir in Patients With Chronic HCV Infection: 2 Phase 3 Randomized Trials.

Elbasvir/grazoprevir in black adults with hepatitis C virus infection: a pooled analysis of phase 2/3 clinical trials.

Renin secreting tumour: a rare cause of secondary hypertension.

Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial.

A Patient With Jaundice and Malaise.

The combination of simeprevir and sofosbuvir is more effective than that of peginterferon, ribavirin, and sofosbuvir for patients with hepatitis C-related Child's class A cirrhosis.

Daclatasvir and Peginterferon/Ribavirin for Black/African-American and Latino Patients with HCV infection.

Safety profile of boceprevir and telaprevir in chronic hepatitis C: real world experience from HCV-TARGET.

Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.

Hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor.

How Would You Manage This Patient With Nonalcoholic Fatty Liver Disease?

Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more.